TY - JOUR
T1 - Nuclear functions of actin.
AU - Visa, Neus
AU - Percipalle, Piergiorgio
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2010/4/1
Y1 - 2010/4/1
N2 - Actin participates in several essential processes in the cell nucleus. Even though the presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes that require actin have been only recently identified. Actin is part of chromatin remodeling complexes; it is associated with the transcription machineries; it becomes incorporated into newly synthesized ribonucleoproteins; and it influences long-range chromatin organization. As in the cytoplasm, nuclear actin works in conjunction with different types of actin-binding proteins that regulate actin function and bridge interactions between actin and other nuclear components.
AB - Actin participates in several essential processes in the cell nucleus. Even though the presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes that require actin have been only recently identified. Actin is part of chromatin remodeling complexes; it is associated with the transcription machineries; it becomes incorporated into newly synthesized ribonucleoproteins; and it influences long-range chromatin organization. As in the cytoplasm, nuclear actin works in conjunction with different types of actin-binding proteins that regulate actin function and bridge interactions between actin and other nuclear components.
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U2 - 10.1101/cshperspect.a000620
DO - 10.1101/cshperspect.a000620
M3 - Review article
C2 - 20452941
AN - SCOPUS:77956076208
VL - 2
SP - a000620
JO - Cold Spring Harbor perspectives in biology
JF - Cold Spring Harbor perspectives in biology
SN - 1943-0264
IS - 4
ER -