Nuclear functions of actin.

Research output: Contribution to journalReview articlepeer-review


Actin participates in several essential processes in the cell nucleus. Even though the presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes that require actin have been only recently identified. Actin is part of chromatin remodeling complexes; it is associated with the transcription machineries; it becomes incorporated into newly synthesized ribonucleoproteins; and it influences long-range chromatin organization. As in the cytoplasm, nuclear actin works in conjunction with different types of actin-binding proteins that regulate actin function and bridge interactions between actin and other nuclear components.

Original languageEnglish (US)
Pages (from-to)a000620
JournalCold Spring Harbor Perspectives in Biology
Issue number4
StatePublished - Apr 1 2010

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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