Nucleic acid-mutagen interactions: crystal structure of adenylyl-3′,5′-uridine plus 9-aminoacridine

Nadrian C. Seeman, Roberta O. Day, Alexander Rich

Research output: Contribution to journalArticlepeer-review

Abstract

Adenylyl-3', 5'-uridine and 9-aminoacridine cocrystallise in a heavily hydrated monoclinic lattice. The adenine residues are hydrogen bonded with uracil residues and the base pairs are stacked parallel to each other in the crystal with 9-aminoacridine sandwiched directly between them.

Original languageEnglish (US)
Pages (from-to)324-326
Number of pages3
JournalNature
Volume253
Issue number5490
DOIs
StatePublished - 1975

ASJC Scopus subject areas

  • General

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