Nucleotide recognition by macrocyclic receptors

Andrew D. Hamilton, Alex Muehldorf, Suk Kyu Chang, Nalin Pant, Shyamaprosad Goswami, Donna van Engen

Research output: Contribution to journalArticlepeer-review

Abstract

It is shown that complementary positioning of recognition sites (particularly hydrogen bonding, stacking and hydrophobic groups) into a macrocyclic structure can lead to very strong and specific complexation of uncharged organic molecules.

Original languageEnglish (US)
Pages (from-to)27-38
Number of pages12
JournalJournal of Inclusion Phenomena and Molecular Recognition in Chemistry
Volume7
Issue number1
DOIs
StatePublished - Feb 1989

Keywords

  • Molecular recognition
  • barbiturate
  • guanine
  • nucleotide
  • thymine

ASJC Scopus subject areas

  • Food Science
  • General Chemistry
  • Condensed Matter Physics

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