Numerical analysis of the flux and force generated by a correlation ratchet mechanism

Chichia Chiu, Charles S. Peskin

Research output: Contribution to journalArticle

Abstract

The correlation ratchet (CR) has been proposed as a possible mechanism for the operation of biomolecular motors. To test whether a CR mechanism is applicable to any particular motor, it is necessary to evaluate the unloaded velocity and the stall force of the CR mechanism. This paper is concerned with efficient numerical procedures for the determination of these quantities. In particular, the numerical results indicate that the stall force of a CR mechanism is quite limited, despite wide variations of the CR parameters.

Original languageEnglish (US)
Pages (from-to)479-501
Number of pages23
JournalJournal Of Mathematical Biology
Volume44
Issue number5
DOIs
StatePublished - May 2002

Keywords

  • Correlation ratchet
  • Mathematical biology
  • Modeling
  • Numerical analysis
  • Reaction-diffusion equations

ASJC Scopus subject areas

  • Modeling and Simulation
  • Agricultural and Biological Sciences (miscellaneous)
  • Applied Mathematics

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