Obesity and Type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence

D. Leroith; R. Novosyadlyy; E. J. Gallagher; D. Lann; A. Vljayakumar; S. Yakar; Derek Leroith

doi:10.1055/s-2008-1081488

Obesity and Type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence

D. Leroith, R. Novosyadlyy, E. J. Gallagher, D. Lann, A. Vljayakumar, S. Yakar, Derek Leroith

Molecular Pathobiology

Research output: Contribution to journal › Review article › peer-review

Abstract

Both obesity and Type 2 diabetes are independently associated with an increased risk of developing cancer and an increased mortality. The etiology is yet to be determined but insulin resistance and hyperinsulinemia maybe important factors. Hyperglycemia, hyperlipidemia and inflammatory cytokines in addition to the insulin-like growth factors are also possible factors involved in the process.

Original language	English (US)
Pages (from-to)	S4-S6
Journal	Experimental and Clinical Endocrinology and Diabetes
Volume	116
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1055/s-2008-1081488
State	Published - Mar 2008

Keywords

Cancer
Diabetes
Epidemiology
Obesity

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1055/s-2008-1081488

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Leroith, D., Novosyadlyy, R., Gallagher, E. J., Lann, D., Vljayakumar, A., Yakar, S., & Leroith, D. (2008). Obesity and Type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence. Experimental and Clinical Endocrinology and Diabetes, 116(SUPPL. 1), S4-S6. https://doi.org/10.1055/s-2008-1081488

Obesity and Type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence. / Leroith, D.; Novosyadlyy, R.; Gallagher, E. J. et al.
In: Experimental and Clinical Endocrinology and Diabetes, Vol. 116, No. SUPPL. 1, 03.2008, p. S4-S6.

Research output: Contribution to journal › Review article › peer-review

Leroith, D, Novosyadlyy, R, Gallagher, EJ, Lann, D, Vljayakumar, A, Yakar, S & Leroith, D 2008, 'Obesity and Type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence', Experimental and Clinical Endocrinology and Diabetes, vol. 116, no. SUPPL. 1, pp. S4-S6. https://doi.org/10.1055/s-2008-1081488

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Obesity and Type 2 diabetes are associated with an increased risk of developing cancer and a worse prognosis; epidemiological and mechanistic evidence

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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