Obstructive sleep apnea and hypertension; critical overview

Younghoon Kwon; William S. Tzeng; Jiwon Seo; Jeongok Gang Logan; Marijana Tadic; Gen Min Lin; Miguel Angel Martinez-Garcia; Martino Pengo; Xiaoyue Liu; Yeilim Cho; Luciano F. Drager; William Healy; Geu Ru Hong

doi:10.1186/s40885-024-00276-7

Obstructive sleep apnea and hypertension; critical overview

Younghoon Kwon, William S. Tzeng, Jiwon Seo, Jeongok Gang Logan, Marijana Tadic, Gen Min Lin, Miguel Angel Martinez-Garcia, Martino Pengo, Xiaoyue Liu, Yeilim Cho, Luciano F. Drager, William Healy, Geu Ru Hong

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Research output: Contribution to journal › Review article › peer-review

Abstract

Obstructive sleep apnea (OSA) and hypertension are two important modifiable risk factors for cardiovascular disease and mortality. Numerous studies have highlighted the interplay between these two conditions. We provide a critical review of the current literature on the role of the OSA as a risk factor for hypertension and its effect on blood pressure (BP). We discuss several key topics: the effect of OSA on nocturnal BP, BP response to continuous positive airway pressure (CPAP) treatment, CPAP effect on BP in refractory hypertension, the role of OSA in BP variability (BPV), and maladaptive cardiac remodeling mediated by OSA’s effect on BP. Finally, we discuss the unique aspects of ethnicity and social determinants of health on OSA with a focus on Asian populations and the disparity in BP control and cardiovascular outcomes.

Original language	English (US)
Article number	19
Journal	Clinical Hypertension
Volume	30
Issue number	1
DOIs	https://doi.org/10.1186/s40885-024-00276-7
State	Published - Dec 2024

Keywords

Blood pressure
Continuous positive airway pressure
Hypertension
Obstructive sleep apnea

ASJC Scopus subject areas

Internal Medicine
Cardiology and Cardiovascular Medicine

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10.1186/s40885-024-00276-7

Cite this

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title = "Obstructive sleep apnea and hypertension; critical overview",

abstract = "Obstructive sleep apnea (OSA) and hypertension are two important modifiable risk factors for cardiovascular disease and mortality. Numerous studies have highlighted the interplay between these two conditions. We provide a critical review of the current literature on the role of the OSA as a risk factor for hypertension and its effect on blood pressure (BP). We discuss several key topics: the effect of OSA on nocturnal BP, BP response to continuous positive airway pressure (CPAP) treatment, CPAP effect on BP in refractory hypertension, the role of OSA in BP variability (BPV), and maladaptive cardiac remodeling mediated by OSA{\textquoteright}s effect on BP. Finally, we discuss the unique aspects of ethnicity and social determinants of health on OSA with a focus on Asian populations and the disparity in BP control and cardiovascular outcomes.",

keywords = "Blood pressure, Continuous positive airway pressure, Hypertension, Obstructive sleep apnea",

author = "Younghoon Kwon and Tzeng, {William S.} and Jiwon Seo and Logan, {Jeongok Gang} and Marijana Tadic and Lin, {Gen Min} and Martinez-Garcia, {Miguel Angel} and Martino Pengo and Xiaoyue Liu and Yeilim Cho and Drager, {Luciano F.} and William Healy and Hong, {Geu Ru}",

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year = "2024",

month = dec,

doi = "10.1186/s40885-024-00276-7",

language = "English (US)",

volume = "30",

journal = "Clinical Hypertension",

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T1 - Obstructive sleep apnea and hypertension; critical overview

AU - Kwon, Younghoon

AU - Tzeng, William S.

AU - Seo, Jiwon

AU - Logan, Jeongok Gang

AU - Tadic, Marijana

AU - Lin, Gen Min

AU - Martinez-Garcia, Miguel Angel

AU - Pengo, Martino

AU - Liu, Xiaoyue

AU - Cho, Yeilim

AU - Drager, Luciano F.

AU - Healy, William

AU - Hong, Geu Ru

PY - 2024/12

Y1 - 2024/12

N2 - Obstructive sleep apnea (OSA) and hypertension are two important modifiable risk factors for cardiovascular disease and mortality. Numerous studies have highlighted the interplay between these two conditions. We provide a critical review of the current literature on the role of the OSA as a risk factor for hypertension and its effect on blood pressure (BP). We discuss several key topics: the effect of OSA on nocturnal BP, BP response to continuous positive airway pressure (CPAP) treatment, CPAP effect on BP in refractory hypertension, the role of OSA in BP variability (BPV), and maladaptive cardiac remodeling mediated by OSA’s effect on BP. Finally, we discuss the unique aspects of ethnicity and social determinants of health on OSA with a focus on Asian populations and the disparity in BP control and cardiovascular outcomes.

AB - Obstructive sleep apnea (OSA) and hypertension are two important modifiable risk factors for cardiovascular disease and mortality. Numerous studies have highlighted the interplay between these two conditions. We provide a critical review of the current literature on the role of the OSA as a risk factor for hypertension and its effect on blood pressure (BP). We discuss several key topics: the effect of OSA on nocturnal BP, BP response to continuous positive airway pressure (CPAP) treatment, CPAP effect on BP in refractory hypertension, the role of OSA in BP variability (BPV), and maladaptive cardiac remodeling mediated by OSA’s effect on BP. Finally, we discuss the unique aspects of ethnicity and social determinants of health on OSA with a focus on Asian populations and the disparity in BP control and cardiovascular outcomes.

KW - Blood pressure

KW - Continuous positive airway pressure

KW - Hypertension

KW - Obstructive sleep apnea

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U2 - 10.1186/s40885-024-00276-7

DO - 10.1186/s40885-024-00276-7

M3 - Review article

AN - SCOPUS:85200202543

SN - 2056-5909

VL - 30

JO - Clinical Hypertension

JF - Clinical Hypertension

IS - 1

M1 - 19

ER -

Obstructive sleep apnea and hypertension; critical overview

Abstract

Keywords

ASJC Scopus subject areas

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