Of mice and malaria mutants: Unravelling the genetics of drug resistance using rodent malaria models

J. M R Carlton; Karen Hayton; P. V L Cravo; David Walliker

doi:10.1016/S1471-4922(01)01899-2

Of mice and malaria mutants: Unravelling the genetics of drug resistance using rodent malaria models

J. M R Carlton, Karen Hayton, P. V L Cravo, David Walliker

Research output: Contribution to journal › Review article › peer-review

Abstract

It is well recognized that drug resistance is the most significant obstacle to gaining effective malaria control. Despite the enormous advances in the knowledge of the biochemistry and molecular biology of malaria parasites, only a few genes determining resistance to the commonly used drugs have been identified. The idea that rodent malaria parasites should be exploited more widely for such work, in view of the practical problems of studying this subject experimentally in human malaria, is presented.

Original language	English (US)
Pages (from-to)	236-242
Number of pages	7
Journal	Trends in Parasitology
Volume	17
Issue number	5
DOIs	https://doi.org/10.1016/S1471-4922(01)01899-2
State	Published - 2001

ASJC Scopus subject areas

Parasitology
Infectious Diseases

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