O kompaktizatsii DNK v razbavlennykh polimernykh rastvorakh.

A. I. Grosberg; I. I. Erukhimovich; E. I. Shakhnovich

O kompaktizatsii DNK v razbavlennykh polimernykh rastvorakh.

Translated title of the contribution: On DNA compaction in diluted polymeric solutions

A. I. Grosberg, I. I. Erukhimovich, E. I. Shakhnovich

Research output: Contribution to journal › Article › peer-review

Abstract

Causes of compactization of double helical molecule of DNA in polyethylene glycol (PEG) solution are considered. The compactization mechanism is shown to be based on the displacement of PEG coil from the initiated globular DNA particle. An efficient virial coefficient of the interaction between DNA monomers through PEG chains is calculated. An efficient theta-point is found from PEG concentration. The experimental relationship between PEG critical concentration responding to the onset of compactization and PEG molecular weight is analysed. The absence of DNA compactization and PEG molecular weight is analysed. The absence of DNA compactization with PEG of low molecular weight is explained. Theoretical works on DNA compactization are reviewed.

Translated title of the contribution	On DNA compaction in diluted polymeric solutions
Original language	Russian
Pages (from-to)	415-420
Number of pages	6
Journal	Biofizika
Volume	26
Issue number	3
State	Published - May 1981

ASJC Scopus subject areas

General Medicine

Cite this

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abstract = "Causes of compactization of double helical molecule of DNA in polyethylene glycol (PEG) solution are considered. The compactization mechanism is shown to be based on the displacement of PEG coil from the initiated globular DNA particle. An efficient virial coefficient of the interaction between DNA monomers through PEG chains is calculated. An efficient theta-point is found from PEG concentration. The experimental relationship between PEG critical concentration responding to the onset of compactization and PEG molecular weight is analysed. The absence of DNA compactization and PEG molecular weight is analysed. The absence of DNA compactization with PEG of low molecular weight is explained. Theoretical works on DNA compactization are reviewed.",

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year = "1981",

month = may,

language = "Russian",

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pages = "415--420",

journal = "Biofizika",

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T1 - O kompaktizatsii DNK v razbavlennykh polimernykh rastvorakh.

AU - Grosberg, A. I.

AU - Erukhimovich, I. I.

AU - Shakhnovich, E. I.

PY - 1981/5

Y1 - 1981/5

N2 - Causes of compactization of double helical molecule of DNA in polyethylene glycol (PEG) solution are considered. The compactization mechanism is shown to be based on the displacement of PEG coil from the initiated globular DNA particle. An efficient virial coefficient of the interaction between DNA monomers through PEG chains is calculated. An efficient theta-point is found from PEG concentration. The experimental relationship between PEG critical concentration responding to the onset of compactization and PEG molecular weight is analysed. The absence of DNA compactization and PEG molecular weight is analysed. The absence of DNA compactization with PEG of low molecular weight is explained. Theoretical works on DNA compactization are reviewed.

AB - Causes of compactization of double helical molecule of DNA in polyethylene glycol (PEG) solution are considered. The compactization mechanism is shown to be based on the displacement of PEG coil from the initiated globular DNA particle. An efficient virial coefficient of the interaction between DNA monomers through PEG chains is calculated. An efficient theta-point is found from PEG concentration. The experimental relationship between PEG critical concentration responding to the onset of compactization and PEG molecular weight is analysed. The absence of DNA compactization and PEG molecular weight is analysed. The absence of DNA compactization with PEG of low molecular weight is explained. Theoretical works on DNA compactization are reviewed.

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M3 - Article

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SN - 0006-3029

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EP - 420

JO - Biofizika

JF - Biofizika

IS - 3

ER -

O kompaktizatsii DNK v razbavlennykh polimernykh rastvorakh.

Abstract

ASJC Scopus subject areas

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