Opiate receptor avidity (B'(max)/K(D)), was measured in the subcortex of nine females (five healthy subjects, four Alzheimer patients) and 15 males (seven healthy subjects, eight Alzheimer patients), 51-75 years of age, with the opiate receptor antagonist 6-deoxy-6-β-[18F]fluoronaltrexone (cyclofoxy, CF) and a positron emission tomograph. CF avidity was 27.5% less in the thalamus of healthy women compared to healthy men and 48.5% less in Alzheimer disease female patients compared to male patients. (C) 2000 Wiley-Liss, Inc.
|Original language||English (US)|
|Number of pages||4|
|State||Published - 2000|
- Basal ganglia
- Positron emission tomography
ASJC Scopus subject areas
- Cellular and Molecular Neuroscience