TY - JOUR
T1 - Opiate receptor avidity in the thalamus is sexually dimorphic in the elderly
AU - Woodson, Walter
AU - Farb, Claudia R.
AU - Ledoux, Joseph E.
PY - 2000
Y1 - 2000
N2 - Opiate receptor avidity (B'(max)/K(D)), was measured in the subcortex of nine females (five healthy subjects, four Alzheimer patients) and 15 males (seven healthy subjects, eight Alzheimer patients), 51-75 years of age, with the opiate receptor antagonist 6-deoxy-6-β-[18F]fluoronaltrexone (cyclofoxy, CF) and a positron emission tomograph. CF avidity was 27.5% less in the thalamus of healthy women compared to healthy men and 48.5% less in Alzheimer disease female patients compared to male patients. (C) 2000 Wiley-Liss, Inc.
AB - Opiate receptor avidity (B'(max)/K(D)), was measured in the subcortex of nine females (five healthy subjects, four Alzheimer patients) and 15 males (seven healthy subjects, eight Alzheimer patients), 51-75 years of age, with the opiate receptor antagonist 6-deoxy-6-β-[18F]fluoronaltrexone (cyclofoxy, CF) and a positron emission tomograph. CF avidity was 27.5% less in the thalamus of healthy women compared to healthy men and 48.5% less in Alzheimer disease female patients compared to male patients. (C) 2000 Wiley-Liss, Inc.
KW - 6-deoxy-6-β[F]fluoronaltrexone
KW - Basal ganglia
KW - Positron emission tomography
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U2 - 10.1002/1098-2396(200011)38:2<226::aid-syn13>3.0.co;2-%23
DO - 10.1002/1098-2396(200011)38:2<226::aid-syn13>3.0.co;2-%23
M3 - Article
C2 - 11018796
AN - SCOPUS:0033774887
SN - 0887-4476
VL - 38
SP - 226
EP - 229
JO - Synapse
JF - Synapse
IS - 2
ER -