Optical Coherence Tomography and Glaucoma

Alexi Geevarghese, Gadi Wollstein, Hiroshi Ishikawa, Joel S. Schuman

Research output: Contribution to journalReview articlepeer-review


Early detection and monitoring are critical to the diagnosis and management of glaucoma, a progressive optic neuropathy that causes irreversible blindness. Optical coherence tomography (OCT) has become a commonly utilized imaging modality that aids in the detection and monitoring of structural glaucomatous damage. Since its inception in 1991, OCT has progressed through multiple iterations, from time-domain OCT, to spectral-domain OCT, to swept-source OCT, all of which have progressively improved the resolution and speed of scans. Even newer technological advancements and OCT applications, such as adaptive optics, visible-light OCT, and OCT-angiography, have enriched the use of OCT in the evaluation of glaucoma. This article reviews current commercial and state-of-the-art OCT technologies and analytic techniques in the context of their utility for glaucoma diagnosis and management, as well as promising future directions.

Original languageEnglish (US)
Pages (from-to)693-726
Number of pages34
JournalAnnual review of vision science
StatePublished - Sep 15 2021


  • Glaucoma
  • OCT
  • imaging
  • optical coherence tomography

ASJC Scopus subject areas

  • General Medicine


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