Optical coherence tomography in glaucoma

Allison K. Ungar, Gadi Wollstein, Joel S. Schuman

Research output: Chapter in Book/Report/Conference proceedingChapter


Glaucoma is the second leading cause of blindness worldwide. It is characterized by the accelerated death of retinal ganglion cells and is presented as progressive functional damage in the visual field. Disease detection is dependent on the clinical capabilities of the eye care provider identifying structural changes in the retina and optic nerve head region compatible with glaucoma. The first-line diagnostic tools for identifying glaucoma are clinical examination with direct or indirect ophthalmoscopy and/or stereoscopic optic nerve head photographs. Unfortunately, these tools are prone to high intra- and inter-observer variability. A number of imaging devices have been incorporated into clinical practice with the goal of early detection and quantification of structural glaucomatous changes in the retinal nerve fiber layer and optic nerve head. One of the commercially available glaucoma imaging devices is optical coherence tomography (OCT).OCT generates cross-sectional and three-dimensional images of retinal structures.Its application in glaucoma diagnostics and monitoring will be discussed in this chapter.

Original languageEnglish (US)
Title of host publicationDiagnostic Technologies in Ophthalmology
PublisherBentham Science Publishers Ltd.
Number of pages31
ISBN (Print)9781608054312
StatePublished - 2012


  • Glaucoma diagnosis
  • Glaucoma monitoring
  • Glaucoma progression
  • Imaging
  • Laser
  • Macula
  • Optic nerve head
  • Optical coherence tomography
  • Peripapillary area
  • Pre-perimetric glaucoma
  • Resolution
  • Retina
  • Retinal nerve fibre layer
  • Spectral domain
  • Time domain

ASJC Scopus subject areas

  • General Medicine


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