@inproceedings{dc1156ee7da54b348f898befe842a416,
title = "Optical fluorescence tomography with the equation of radiative transfer for molecular imaging",
abstract = "Optical fluorescence tomography recovers the spatial distribution of light emitting fluorophores inside a highly scattering medium. The quantification of a non-uniform quantum yield and fluorophore absorption distribution is of major interest in molecular imaging of biological tissue. We have developed a fluorescence image reconstruction code that is based on the particle transport equation. Since the algorithm does not rely on the diffusion approximation it promises to yield more accurate results in highly absorbing media or media with small geometries. We show that the code can be employed in a two-stage reconstruction process to obtain images of the fluorophore absorption and of the quantum yield.",
keywords = "Discrete-ordinates method, Equation of radiative transfer, Finite-difference method, Fluorescence tomography, Image reconstruction, Molecular imaging, Quantum yield",
author = "Klose, {Alexander D.} and Hielscher, {Andreas H.}",
note = "Copyright: Copyright 2008 Elsevier B.V., All rights reserved.; PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Optical Tomography and Spectroscopy of Tissue V ; Conference date: 26-01-2003 Through 29-01-2003",
year = "2003",
doi = "10.1117/12.478227",
language = "English (US)",
volume = "4955",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
pages = "219--225",
booktitle = "PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Optical Tomography and Spectroscopy of Tissue V",
}