Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints

A. H. Hielscher, A. D. Klose, A. Scheel, A. Bluestone, J. M. Lasker, B. Moa-Anderson, J. M. Masciotti, U. Netz, J. Beuthan, M. Stewart, G. Abdoulaev

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Over the last decade the field of diffuse optical tomography (DOT) has seen considerable advances and is now close to becoming a clinically viable medical imaging modality. Imaging of dynamic changes in blood parameters, functional brain imaging, and breast imaging are the most advanced application areas of this novel technique. In this study we focus on difficulties that are encountered when DOT is employed for imaging small tissue volumes. These problems arise, for example, in studies involving small animals, such as rats or mice, or human finger joints. In these cases widely accepted image reconstruction schemes that rely on the diffusion approximation have limited applicability, and more advanced model-based iterative image reconstructions methods that make use of the equation of radiative transfer promise more accurate results.

    Original languageEnglish (US)
    Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
    Subtitle of host publicationMacro to Nano
    Pages1467-1470
    Number of pages4
    StatePublished - 2004
    Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States
    Duration: Apr 15 2004Apr 18 2004

    Publication series

    Name2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
    Volume2

    Other

    Other2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
    CountryUnited States
    CityArlington, VA
    Period4/15/044/18/04

    ASJC Scopus subject areas

    • Engineering(all)

    Fingerprint Dive into the research topics of 'Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints'. Together they form a unique fingerprint.

    Cite this