Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints

A. H. Hielscher; A. D. Klose; A. Scheel; A. Bluestone; J. M. Lasker; B. Moa-Anderson; J. M. Masciotti; U. Netz; J. Beuthan; M. Stewart; G. Abdoulaev

Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints

A. H. Hielscher, A. D. Klose, A. Scheel, A. Bluestone, J. M. Lasker, B. Moa-Anderson, J. M. Masciotti, U. Netz, J. Beuthan, M. Stewart, G. Abdoulaev

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Over the last decade the field of diffuse optical tomography (DOT) has seen considerable advances and is now close to becoming a clinically viable medical imaging modality. Imaging of dynamic changes in blood parameters, functional brain imaging, and breast imaging are the most advanced application areas of this novel technique. In this study we focus on difficulties that are encountered when DOT is employed for imaging small tissue volumes. These problems arise, for example, in studies involving small animals, such as rats or mice, or human finger joints. In these cases widely accepted image reconstruction schemes that rely on the diffusion approximation have limited applicability, and more advanced model-based iterative image reconstructions methods that make use of the equation of radiative transfer promise more accurate results.

Original language	English (US)
Title of host publication	2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publication	Macro to Nano
Pages	1467-1470
Number of pages	4
State	Published - 2004
Event	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States Duration: Apr 15 2004 → Apr 18 2004

Publication series

Name	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume	2

Other

Other	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/Territory	United States
City	Arlington, VA
Period	4/15/04 → 4/18/04

ASJC Scopus subject areas

General Engineering

Cite this

Hielscher, A. H., Klose, A. D., Scheel, A., Bluestone, A., Lasker, J. M., Moa-Anderson, B., Masciotti, J. M., Netz, U., Beuthan, J., Stewart, M., & Abdoulaev, G. (2004). Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 1467-1470). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 2).

Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints. / Hielscher, A. H.; Klose, A. D.; Scheel, A. et al.
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004. p. 1467-1470 (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hielscher, AH, Klose, AD, Scheel, A, Bluestone, A, Lasker, JM, Moa-Anderson, B, Masciotti, JM, Netz, U, Beuthan, J, Stewart, M & Abdoulaev, G 2004, Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints. in 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, vol. 2, pp. 1467-1470, 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, Arlington, VA, United States, 4/15/04.

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Optical tomographic imaging of small tissue volumes: From rat brains to human finger joints

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