TY - GEN
T1 - Optimal control mechanism involving the human kidney
AU - Jiang, Yu
AU - Chemudupati, Srinivasa
AU - Jorgensen, Jan Morup
AU - Jiang, Zhong Ping
AU - Peskin, Charles S.
PY - 2011
Y1 - 2011
N2 - In this paper we study the control mechanism that regulates water and the concentration of sodium in human body. For this reverse engineering problem, a control system model is developed using a modification of the standard LQR theory. The control law derived in this paper reflects the realistic situation in which the body is in a supine position or a standing position, and also takes into account feedback time lag. The theoretical model is validated by experimental data fitting. Both computer simulations and experimental data fitting show that the proposed model can capture the main trends of water and salt outputs, and achieve tight control of the plasma concentration of salt as recorded in the experiment[7].
AB - In this paper we study the control mechanism that regulates water and the concentration of sodium in human body. For this reverse engineering problem, a control system model is developed using a modification of the standard LQR theory. The control law derived in this paper reflects the realistic situation in which the body is in a supine position or a standing position, and also takes into account feedback time lag. The theoretical model is validated by experimental data fitting. Both computer simulations and experimental data fitting show that the proposed model can capture the main trends of water and salt outputs, and achieve tight control of the plasma concentration of salt as recorded in the experiment[7].
UR - http://www.scopus.com/inward/record.url?scp=84860653557&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860653557&partnerID=8YFLogxK
U2 - 10.1109/CDC.2011.6160282
DO - 10.1109/CDC.2011.6160282
M3 - Conference contribution
AN - SCOPUS:84860653557
SN - 9781612848006
T3 - Proceedings of the IEEE Conference on Decision and Control
SP - 3688
EP - 3693
BT - 2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011
Y2 - 12 December 2011 through 15 December 2011
ER -