Optimal control mechanism involving the human kidney

Yu Jiang, Srinivasa Chemudupati, Jan Morup Jorgensen, Zhong Ping Jiang, Charles S. Peskin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper we study the control mechanism that regulates water and the concentration of sodium in human body. For this reverse engineering problem, a control system model is developed using a modification of the standard LQR theory. The control law derived in this paper reflects the realistic situation in which the body is in a supine position or a standing position, and also takes into account feedback time lag. The theoretical model is validated by experimental data fitting. Both computer simulations and experimental data fitting show that the proposed model can capture the main trends of water and salt outputs, and achieve tight control of the plasma concentration of salt as recorded in the experiment[7].

Original languageEnglish (US)
Title of host publication2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011
Pages3688-3693
Number of pages6
DOIs
StatePublished - 2011
Event2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011 - Orlando, FL, United States
Duration: Dec 12 2011Dec 15 2011

Publication series

NameProceedings of the IEEE Conference on Decision and Control
ISSN (Print)0191-2216

Other

Other2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011
CountryUnited States
CityOrlando, FL
Period12/12/1112/15/11

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Modeling and Simulation
  • Control and Optimization

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