Optimal control NMR differentiation between fast and slow sodium

Jae Seung Lee, Ravinder R. Regatte, Alexej Jerschow

Research output: Contribution to journalArticlepeer-review

Abstract

Sodium ions in tissues and organs may experience motion on a variety of timescales, leading to NMR relaxation effects with quadrupolar coupling as the primary mechanism. The various effects that this fluctuating interaction has on spin dynamics can be exploited for distinguishing slow sodium ions from fast ones. Techniques such as triple-quantum filtering have been used for this purpose in the past. In this work we present optimal pulses which significantly improve the selectivity towards slow-tumbling sodium. These pulses can also be modified for robustness against magnetic field inhomogeneities, and could hence also become useful as MRI contrast methods.

Original languageEnglish (US)
Pages (from-to)331-336
Number of pages6
JournalChemical Physics Letters
Volume494
Issue number4-6
DOIs
StatePublished - Jul 19 2010

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

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