Optimization of prostate biopsy: Review of technique and complications

Marc A. Bjurlin, James S. Wysock, Samir S. Taneja

Research output: Contribution to journalReview articlepeer-review


A 12-core systematic biopsy that incorporates apical and far-lateral cores in the template distribution allows maximal cancer detection and avoidance of a repeat biopsy while minimizing the detection of insignificant prostate cancers. Magnetic resonance imaging-guided prostate biopsy has an evolving role in both initial and repeat prostate biopsy strategies, potentially improving sampling efficiency, increasing the detection of clinically significant cancers, and reducing the detection of insignificant cancers. Hematuria, hematospermia, and rectal bleeding are common complications of prostate needle biopsy, but are generally self-limiting and well tolerated. All men should receive antimicrobial prophylaxis before biopsy.

Original languageEnglish (US)
Pages (from-to)299-313
Number of pages15
JournalUrologic Clinics of North America
Issue number2
StatePublished - May 2014


  • Biopsy core number
  • Magnetic resonance imaging
  • Prostate needle biopsy
  • Quinolone-reistant infection

ASJC Scopus subject areas

  • Urology


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