Palladium-Catalyzed Atom-Transfer Radical Cyclization at Remote Unactivated C(sp3)−H Sites: Hydrogen-Atom Transfer of Hybrid Vinyl Palladium Radical Intermediates

Maxim Ratushnyy, Marvin Parasram, Yang Wang, Vladimir Gevorgyan

Research output: Contribution to journalArticlepeer-review

Abstract

A novel mild, visible-light-induced palladium-catalyzed hydrogen atom translocation/atom-transfer radical cyclization (HAT/ATRC) cascade has been developed. This protocol involves a 1,5-HAT process of previously unknown hybrid vinyl palladium radical intermediates, thus leading to iodomethyl carbo- and heterocyclic structures.

Original languageEnglish (US)
Pages (from-to)2712-2715
Number of pages4
JournalAngewandte Chemie - International Edition
Volume57
Issue number10
DOIs
StatePublished - Mar 1 2018

Keywords

  • cyclizations
  • hydrogen-atom transfer
  • palladium
  • photochemistry
  • radicals

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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