Abstract
The cyclization of γ, δ-unsaturated tertiary hydroperoxides in the presence of a palladium(II) catalyst afforded 1,2-dioxanes resembling biologically active natural products. A variety of substrates were screened, and synthetic manipulations were accomplished to construct compounds with structural similarity to antimalarial targets.
Original language | English (US) |
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Pages (from-to) | 3290-3293 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 11 |
Issue number | 15 |
DOIs | |
State | Published - Aug 6 2009 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry