Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects

Thomas C. Williams, Heinrich Kroukamp, Xin Xu, Elizabeth L.I. Wightman, Briardo Llorente, Anthony R. Borneman, Alexander C. Carpenter, Niel Van Wyk, Felix Meier, Thomas R.V. Collier, Monica I. Espinosa, Elizabeth L. Daniel, Roy S.K. Walker, Yizhi Cai, Helena K.M. Nevalainen, Natalie C. Curach, Ira W. Deveson, Timothy R. Mercer, Daniel L. Johnson, Leslie A. MitchellJoel S. Bader, Giovanni Stracquadanio, Jef D. Boeke, Hugh D. Goold, Isak S. Pretorius, Ian T. Paulsen

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