Pattern-Based Detection of Different Proteins Using an Array of Fluorescent Protein Surface Receptors

Laura Baldini; Andrew J. Wilson; Jason Hong; Andrew D. Hamilton

doi:10.1021/ja039562j

Pattern-Based Detection of Different Proteins Using an Array of Fluorescent Protein Surface Receptors

Laura Baldini, Andrew J. Wilson, Jason Hong, Andrew D. Hamilton

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A small library of porphyrin derivatives whose fluorescence emission changes on binding to protein surfaces has been developed as a protein "fingerprinting" array. When incubated with different proteins, the array yields a characteristic response, specific for every protein analyte. At the same time, this design allows for the rapid screening of the porphyrin library for the identification of high affinity protein surface ligands.

Original language	English (US)
Pages (from-to)	5656-5657
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	126
Issue number	18
DOIs	https://doi.org/10.1021/ja039562j
State	Published - May 12 2004

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja039562j

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Pattern-Based Detection of Different Proteins Using an Array of Fluorescent Protein Surface Receptors

Abstract

ASJC Scopus subject areas

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