Abstract
Heat-shock proteins (Hsps) maintain homeostasis by assisting protein folding, and the transcriptional regulation of Hsp-coding genes has long been under study. Sawarkar et al. (2012) now report in Cell that Hsp90 is itself a transcriptional regulator required for RNA polymerase pausing, contributing to rapid, robust induction of many genes.
Original language | English (US) |
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Pages (from-to) | 905-906 |
Number of pages | 2 |
Journal | Developmental Cell |
Volume | 22 |
Issue number | 5 |
DOIs | |
State | Published - May 15 2012 |
ASJC Scopus subject areas
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- Developmental Biology
- Cell Biology