Pausing on the Path to Robustness

Research output: Contribution to journalShort surveypeer-review

Abstract

Heat-shock proteins (Hsps) maintain homeostasis by assisting protein folding, and the transcriptional regulation of Hsp-coding genes has long been under study. Sawarkar et al. (2012) now report in Cell that Hsp90 is itself a transcriptional regulator required for RNA polymerase pausing, contributing to rapid, robust induction of many genes.

Original languageEnglish (US)
Pages (from-to)905-906
Number of pages2
JournalDevelopmental Cell
Volume22
Issue number5
DOIs
StatePublished - May 15 2012

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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