Peptide and protein recognition by designed molecules

Mark W. Peczuh, Andrew D. Hamilton

Research output: Contribution to journalArticlepeer-review


At present, there is a growing interest in understanding and manipulating protein-protein interactions due to their central importance in many biological processes. This article details current strategies for binding protein surfaces with emphasis on the use of designed molecules. Examples are given that indicate the great promise in the design of small molecules to bind protein surfaces.

Original languageEnglish (US)
Pages (from-to)2479-2494
Number of pages16
JournalChemical reviews
Issue number7
StatePublished - Jul 2000

ASJC Scopus subject areas

  • General Chemistry


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