Abstract
At present, there is a growing interest in understanding and manipulating protein-protein interactions due to their central importance in many biological processes. This article details current strategies for binding protein surfaces with emphasis on the use of designed molecules. Examples are given that indicate the great promise in the design of small molecules to bind protein surfaces.
Original language | English (US) |
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Pages (from-to) | 2479-2494 |
Number of pages | 16 |
Journal | Chemical reviews |
Volume | 100 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2000 |
ASJC Scopus subject areas
- General Chemistry