Abstract
Radically unconventional: Natural products with di- and trichloromethyl groups and trifluoromethylated pharmaceuticals and agrochemicials are interesting compounds, often with intriguing properties. These types of compounds can be prepared by the direct perhaloalkylation of carbonyl compounds in which enolate reactivity and radical reactivity are merged (see scheme; Bn=benzyl).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4542-4544 |
| Number of pages | 3 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 50 |
| Issue number | 20 |
| DOIs | |
| State | Published - May 9 2011 |
Keywords
- electron transfer
- enols
- perhaloalkylation
- radical reactions
- valence tautomerism
ASJC Scopus subject areas
- Catalysis
- General Chemistry