This study was undertaken to histologically evaluate the effects of a periodontal ligament injection of local anesthetic containing various concentrations of epinephrine on pulp tissue. Intraligamental injections of 2% lidocaine with 1:100,000 and 1:50,000 epinephrines were administered to the canine and molar teeth of cats. The animals were killed at 0, 30, and 60 min and at 1, 3, and 7 days after injection. Histological examination showed that no pathological changes in the pulps occurred in any of the experimental teeth.
ASJC Scopus subject areas