Periodontitis, edentulism and glycemic control in patients with type 2 diabetes: A cross-sectional study

Zuila Albuquerque Taboza, Katia Linhares Costa, Virginia Régia Silveira, Flavia Aparecida Furlaneto, Renan Montenegro, Stefanie Russell, Ananda Dasanayake, Rodrigo O. Rego

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives To compare the glycemic control in non-smoking patients with type 2 diabetes according to their periodontal and dental status. Research design and methods This cross-sectional study investigated patients previously diagnosed with type 2 diabetes and under antidiabetic medication. Clinical data and fasting blood glucose (FBG) levels were collected from medical and dental records. Patients were divided into three groups according to dental and periodontal diagnosis: no or mild periodontitis (NO/MILD, n=96), moderate or severe periodontitis (MOD/SEV, n=74) and edentulous (n=141). FBG levels were compared between groups. Logistic regression was also applied to estimate the OR of presenting hyperglycemia. Results Edentulous patients had significantly higher FBG levels of 155.7±70.9 (mean±SD mg/dL) than those in the MOD/SEV (136.6±33.8) and the NO/MILD (123.1±36.7) groups. Differences between the latter two groups were also significant. Edentulous patients had adjusted ORs of 4.53, 4.27 and 3.95 of having FBG≥126, ≥150 and ≥180 mg/dL, respectively, in comparison with NO/MILD group. The MOD/SEV group also presented significant odds of having FBG≥126 mg/dL (OR=2.66) and ≥150 mg/dL (OR=2.45) than the NO/MILD group. Conclusions Patients in the MOD/SEV group had worse glycemic control than the ones in the NO/MILD group. However, edentulous patients presented higher glycemic levels than both dentate groups, and also presented with higher odds of having hyperglycemia.

Original languageEnglish (US)
Article numbere000453
JournalBMJ Open Diabetes Research and Care
Volume6
Issue number1
DOIs
StatePublished - Mar 1 2018

Keywords

  • fasting blood glucose
  • glycemic control
  • oral health issues

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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