@article{a1296e2604844ed0a476da47fe816a21,
title = "Peripapillary Schisis in Glaucoma Patients With Narrow Angles and Increased Intraocular Pressure",
abstract = "Purpose: To describe two cases of peripapillary retinal schisis in patients with glaucoma without evidence of optic nerve pits, pseudopits, or X-linked retinoschisis. Design: Two observational case reports and literature review. Methods: Imaging of the peripapillary nerve fiber layer and schisis cavities was completed in two patients, and one patient was followed over time. Results: The first patient, diagnosed with narrow angle glaucoma, was noted to have peripapillary schisis in the right eye with matching changes on visual field and optical coherence tomographic (OCT) results. Follow-up examination revealed that the schisis disappeared in the right eye while appearing in the left. The findings were verified with high-speed ultra-high-resolution OCT performed in both eyes. The second case involved a patient with anatomically narrow angles, high intraocular pressure (IOP), and peripapillary schisis extending into the macula. Conclusions: Peripapillary retinoschisis may represent a unique sequelae of intraocular fluctuations in patients with uncontrolled glaucoma. Further studies are needed to better understand this disease process.",
author = "Kahook, {Malik Y.} and Noecker, {Robert J.} and Hiroshi Ishikawa and Gadi Wollstein and Larry Kagemann and Maciej Wojtkowski and Duker, {Jay S.} and Srinivasan, {Vivek J.} and Fujimoto, {James G.} and Schuman, {Joel S.}",
note = "Funding Information: This study was supported in part by National Institutes of Health contracts R01-EY013178-06, RO1-EY11289-20, and P30-EY008098, The Eye and Ear Foundation, Pittsburgh, Pennsylvania, an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York, National Science Foundation contract ECS-0119452, Air Force Office of Scientific Research contract FA9550-040-1-0011, and Medical Free Electron Laser Program contract FA9550-040-1-0046. Dr Fujimoto and Dr Schuman received royalties from intellectual property licensed by MIT to Carl Zeiss Meditec. Dr Schuman received research support from Carl Zeiss Meditec. Involved in design and conduct of study (M.Y.K., J.S.S.); collection of data (M.Y.K., G.W., H.I.); management (M.Y.K., J.S.S.); analysis (M.Y.K., H.I., G.W., V.J.S., M.W.); interpretation of the data (M.Y.K., H.I., G.W., V.J.S., M.W.); and preparation, review, or approval of the manuscript (M.Y.K., R.J.N., J.S.S., J.G.F., J.S.D.). ",
year = "2007",
month = apr,
doi = "10.1016/j.ajo.2006.10.054",
language = "English (US)",
volume = "143",
pages = "697--699.e1",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier Inc.",
number = "4",
}