Purpose: To determine the anatomical and physiological response to laser iridectomy (PI) in eyes with pigmentary dispersion syndrome (PDS) and pigmentary glaucoma (PG). Methods: 5 patients with pigmentary glaucoma and 2 patients with pigmentary dispersion syndrome underwent YAG laser iridectomy in one eye. Both eyes of each patient were examined with Ultrasound Biomicroscope (UBM) imaging, by tonography, after brief vigorous exercise sessions for pigment release, and for number of iris transillumination defects (TID) preoperatively and at 1, 6 and 12 months postoperatively. Intraocular pressure control was also assessed. Results: 5/7 eyes had a preoperative concave iris contour on UBM that resolved after PI. 2/7 eyes had a flat iris contour pre and postop. 6/7 treated eyes showed a decrease in exercise-induced pigment release compared with 2/7 untreated eyes. No treated eyes developed more TID compared to 2/7 untreated eyes. 4/7 treated eyes required an escalation of medications after PI, compared to 3/7 untreated eyes. Conclusions: Iridectomy is successful in altering iris contour, decreasing exercise induced pigment release, and preventing TID development in eyes with PG and PDS. However, IOP control was not affected during 1 year follow up.
|Original language||English (US)|
|Journal||Investigative Ophthalmology and Visual Science|
|State||Published - Feb 15 1996|
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience