TY - JOUR
T1 - Persistence of Cloquet's Canal in Normal Healthy Eyes
AU - Kagemann, Larry
AU - Wollstein, Gadi
AU - Ishikawa, Hiroshi
AU - Gabriele, Michelle L.
AU - Srinivasan, Vivek J.
AU - Wojtkowski, Maciej
AU - Duker, Jay S.
AU - Fujimoto, James G.
AU - Schuman, Joel S.
N1 - Funding Information:
Supported in part by NIH contracts R01-EY13178-06, RO1-EY11289-20, P30-EY08098, and P30-EY13078; NSF contract ECS-0119452 and BES-0522845; Air Force Office of Scientific Research contract FA9550-040-1-0011; Medical Free Electron Laser Program contract FA9550-040-1-0046; The Eye and Ear Foundation (Pittsburgh); and an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York.
PY - 2006/11
Y1 - 2006/11
N2 - Purpose: Optic nerve head (ONH) structural imaging with state-of-the-art, high-speed, ultra-high-resolution optical coherence tomography (hsUHR-OCT). Design: Observational cohort study. Methods: ONH centered 3-dimensional (94,371,840 voxel measurements in a 6- × 6- × 1.4-mm tissue volume) hsUHR-OCT data were obtained in one eye from each of six males and nine females normal healthy volunteers (40 ± 9 years of age). The presence of structures projecting anteriorly from the disk into the vitreous was noted. Results: Structures were noted in 14 of 15 (93%) examined eyes, emanating from the rim of the ONH at the nasal inferior sector, presenting as thin tissue meandering into the vitreous. Conclusions: Previous technologies provided limited visualization of ONH structures. The ability to scan the entire disk using 3-dimensional OCT (3D-OCT) in a high-density raster pattern reveals a high frequency of persistence of Cloquet's canal in the normal healthy eye.
AB - Purpose: Optic nerve head (ONH) structural imaging with state-of-the-art, high-speed, ultra-high-resolution optical coherence tomography (hsUHR-OCT). Design: Observational cohort study. Methods: ONH centered 3-dimensional (94,371,840 voxel measurements in a 6- × 6- × 1.4-mm tissue volume) hsUHR-OCT data were obtained in one eye from each of six males and nine females normal healthy volunteers (40 ± 9 years of age). The presence of structures projecting anteriorly from the disk into the vitreous was noted. Results: Structures were noted in 14 of 15 (93%) examined eyes, emanating from the rim of the ONH at the nasal inferior sector, presenting as thin tissue meandering into the vitreous. Conclusions: Previous technologies provided limited visualization of ONH structures. The ability to scan the entire disk using 3-dimensional OCT (3D-OCT) in a high-density raster pattern reveals a high frequency of persistence of Cloquet's canal in the normal healthy eye.
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U2 - 10.1016/j.ajo.2006.05.059
DO - 10.1016/j.ajo.2006.05.059
M3 - Article
C2 - 17056372
AN - SCOPUS:33750044069
SN - 0002-9394
VL - 142
SP - 862
EP - 864
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 5
ER -