Personalized implant therapy: new perspectives in bone remodeling assessment.

Sleiman Razzouk, Cristina Teixeira

Research output: Contribution to journalReview articlepeer-review


Current approaches for immediately loading dental implants rely upon clinical trials and evidence-based practice. Despite their wide utility, these studies have limited predictability because they ignore a whole set of parameters, mainly the environmental parameters that have increasingly influenced the bone biological response. Bone is a very dynamic tissue and its reaction to surgical and functional implant procedures is variable; therefore, bone remodeling must be a key factor in any clinical decision, and a need for reliable tests to evaluate this process is an eventual challenge to implant success. New advances in medicine based upon individual genomic, proteomic and metabolomic studies incorporate the impact of environmental elements, permitting a better targeting of implant therapy. Previously, we proposed a new clinical concept of implant therapy based on personalized bone turnover. Here, we elaborate on current tests and future "omics" biotechnologies to assess the turnover process, hence, providing a realistic approach to individual evaluations of bone remodeling.

Original languageEnglish (US)
Pages (from-to)50-52
Number of pages3
JournalThe New York state dental journal
Issue number4
StatePublished - Jun 2010

ASJC Scopus subject areas

  • General Medicine


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