Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research

Michael M. Engelgau, Emmanuel Peprah, Uchechukwu K.A. Sampson, Helena Mishoe, Ivor J. Benjamin, Pamela S. Douglas, Judith S. Hochman, Paul M. Ridker, Neal Brandes, William Checkley, Sameh El-Saharty, Majid Ezzati, Anselm Hennis, Lixin Jiang, Harlan M. Krumholz, Gabrielle Lamourelle, Julie Makani, K. M.Venkat Narayan, Kwaku Ohene-Frempong, Sharon E. StrausDavid Stuckler, David A. Chambers, Deshirée Belis, Glen C. Bennett, Josephine E. Boyington, Tony L. Creazzo, Janet M. de Jesus, Chitra Krishnamurti, Mia R. Lowden, Antonello Punturieri, Susan T. Shero, Neal S. Young, Shimian Zou, George A. Mensah

Research output: Contribution to journalArticlepeer-review


Almost three-quarters (74%) of all the noncommunicable disease burden is found within low- and middle-income countries. In September 2014, the National Heart, Lung, and Blood Institute held a Global Health Think Tank meeting to obtain expert advice and recommendations for addressing compelling scientific questions for late stage (T4) research—research that studies implementation strategies for proven effective interventions—to inform and guide the National Heart, Lung, and Blood Institute's global health research and training efforts. Major themes emerged in two broad categories: 1) developing research capacity; and 2) efficiently defining compelling scientific questions within the local context. Compelling scientific questions included how to deliver inexpensive, scalable, and sustainable interventions using alternative health delivery models that leverage existing human capital, technologies and therapeutics, and entrepreneurial strategies. These broad themes provide perspectives that inform an overarching strategy needed to reduce the heart, lung, blood, and sleep disorders disease burden and global health disparities.

Original languageEnglish (US)
Pages (from-to)341-348
Number of pages8
JournalGlobal Heart
Issue number4
StatePublished - Dec 2017

ASJC Scopus subject areas

  • Epidemiology
  • Community and Home Care
  • Cardiology and Cardiovascular Medicine


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