Pharmacology of ionotropic glutamate receptors: A structural perspective

Philipp Stawski; Harald Janovjak; Dirk Trauner

doi:10.1016/j.bmc.2010.09.012

Pharmacology of ionotropic glutamate receptors: A structural perspective

Philipp Stawski, Harald Janovjak, Dirk Trauner

Chemistry

Research output: Contribution to journal › Review article › peer-review

Abstract

The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.

Original language	English (US)
Pages (from-to)	7759-7772
Number of pages	14
Journal	Bioorganic and Medicinal Chemistry
Volume	18
Issue number	22
DOIs	https://doi.org/10.1016/j.bmc.2010.09.012
State	Published - Nov 15 2010

Keywords

AMPA receptors
Agonist
Antagonist
Clamshell
Ionotropic glutamate receptors
Kainate receptors
NMDA receptors
Neurotransmitter
Receptor desensitization

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

Access to Document

10.1016/j.bmc.2010.09.012

Cite this

@article{9220d7b27304459fae3355ace14d71a4,

title = "Pharmacology of ionotropic glutamate receptors: A structural perspective",

abstract = "The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.",

keywords = "AMPA receptors, Agonist, Antagonist, Clamshell, Ionotropic glutamate receptors, Kainate receptors, NMDA receptors, Neurotransmitter, Receptor desensitization",

author = "Philipp Stawski and Harald Janovjak and Dirk Trauner",

year = "2010",

month = nov,

day = "15",

doi = "10.1016/j.bmc.2010.09.012",

language = "English (US)",

volume = "18",

pages = "7759--7772",

journal = "Bioorganic and Medicinal Chemistry",

issn = "0968-0896",

publisher = "Elsevier Limited",

number = "22",

}

TY - JOUR

T1 - Pharmacology of ionotropic glutamate receptors

T2 - A structural perspective

AU - Stawski, Philipp

AU - Janovjak, Harald

AU - Trauner, Dirk

PY - 2010/11/15

Y1 - 2010/11/15

N2 - The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.

AB - The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.

KW - AMPA receptors

KW - Agonist

KW - Antagonist

KW - Clamshell

KW - Ionotropic glutamate receptors

KW - Kainate receptors

KW - NMDA receptors

KW - Neurotransmitter

KW - Receptor desensitization

UR - http://www.scopus.com/inward/record.url?scp=78449240498&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78449240498&partnerID=8YFLogxK

U2 - 10.1016/j.bmc.2010.09.012

DO - 10.1016/j.bmc.2010.09.012

M3 - Review article

C2 - 20947363

AN - SCOPUS:78449240498

SN - 0968-0896

VL - 18

SP - 7759

EP - 7772

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

IS - 22

ER -

Pharmacology of ionotropic glutamate receptors: A structural perspective

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this