Pharmacology of ionotropic glutamate receptors: A structural perspective

Philipp Stawski, Harald Janovjak, Dirk Trauner

Research output: Contribution to journalReview articlepeer-review


The impact of structural biology on the design of ligands (agonists, antagonists and modulators) for ionotropic glutamate receptors is reviewed.

Original languageEnglish (US)
Pages (from-to)7759-7772
Number of pages14
JournalBioorganic and Medicinal Chemistry
Issue number22
StatePublished - Nov 15 2010


  • AMPA receptors
  • Agonist
  • Antagonist
  • Clamshell
  • Ionotropic glutamate receptors
  • Kainate receptors
  • NMDA receptors
  • Neurotransmitter
  • Receptor desensitization

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry


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