Phenotypic modulation of pluripotent stem cells (PSCs) induced by microfabrication materials

Ken Ichiro Kamei, Yoshikazu Hirai, Yoshihide Makino, Momoko Yoshioka, Li Liu, Minako Nakajima, Qinghua Yuan, Yong Chen, Osamu Tabata

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Microstructured Photoresist (PR) has been applied for cell culture substrate, but their effects on cell behaviors are still unclear. Here, we evaluated the effects of PR substrates on human induced pluripotent stem cells (hiPSCs), which have a great potential for clinical applications. By comparing two types of epoxy based PRs with and without antimony salt, both PRs have affected on hiPSC viability after culture for seven days.

Original languageEnglish (US)
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages1063-1065
Number of pages3
ISBN (Print)9780979806452
StatePublished - 2012
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: Oct 28 2012Nov 1 2012

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
Country/TerritoryJapan
CityOkinawa
Period10/28/1211/1/12

Keywords

  • Cellular phenotype
  • Gene expression
  • Negative photoresists
  • Pluripotent stem cell
  • Polydimethylsiloxane

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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