Photopharmacological control of lipid function

Johannes Morstein, Dirk Trauner

Research output: Chapter in Book/Report/Conference proceedingChapter


Photopharmacology enables the optical control of biological processes through the use of molecular photoswitches, such as functionalized azobenzenes. In this protocol, we describe general considerations for working with bioactive azobenzene photoswitches. Our approach is exemplified with a photoswitchable sphingosine-1-phosphate analog (PhotoS1P).

Original languageEnglish (US)
Title of host publicationChemical Tools for Imaging, Manipulating, and Tracking Biological Systems
Subtitle of host publicationDiverse Methods for Prokaryotic and Eukaryotic Systems
EditorsDavid M. Chenoweth
PublisherAcademic Press Inc.
Number of pages14
ISBN (Print)9780128201459
StatePublished - 2020

Publication series

NameMethods in enzymology
PublisherAcademic Press Inc.
ISSN (Print)0076-6879


  • Azobenzene
  • GPCR
  • Photochromic ligand
  • Photolipid
  • Photopharmacology
  • Photoswitch
  • Lipids

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry


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