Photopharmacological control of lipid function

Johannes Morstein; Dirk Trauner

doi:10.1016/bs.mie.2020.04.025

Photopharmacological control of lipid function

Johannes Morstein, Dirk Trauner

Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Photopharmacology enables the optical control of biological processes through the use of molecular photoswitches, such as functionalized azobenzenes. In this protocol, we describe general considerations for working with bioactive azobenzene photoswitches. Our approach is exemplified with a photoswitchable sphingosine-1-phosphate analog (PhotoS1P).

Original language	English (US)
Title of host publication	Methods in Enzymology
Editors	David M. Chenoweth
Publisher	Academic Press Inc.
Pages	219-232
Number of pages	14
ISBN (Print)	9780128201459
DOIs	https://doi.org/10.1016/bs.mie.2020.04.025
State	Published - 2020

Publication series

Name	Methods in Enzymology
Volume	638
ISSN (Print)	0076-6879
ISSN (Electronic)	1557-7988

Keywords

Azobenzene
GPCR
Photochromic ligand
Photolipid
Photopharmacology
Photoswitch

ASJC Scopus subject areas

Biochemistry
Molecular Biology

Access to Document

10.1016/bs.mie.2020.04.025

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