Photopharmacological control of lipid function

Johannes Morstein, Dirk Trauner

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Photopharmacology enables the optical control of biological processes through the use of molecular photoswitches, such as functionalized azobenzenes. In this protocol, we describe general considerations for working with bioactive azobenzene photoswitches. Our approach is exemplified with a photoswitchable sphingosine-1-phosphate analog (PhotoS1P).

Original languageEnglish (US)
Title of host publicationMethods in Enzymology
EditorsDavid M. Chenoweth
PublisherAcademic Press Inc.
Pages219-232
Number of pages14
ISBN (Print)9780128201459
DOIs
StatePublished - 2020

Publication series

NameMethods in Enzymology
Volume638
ISSN (Print)0076-6879
ISSN (Electronic)1557-7988

Keywords

  • Azobenzene
  • GPCR
  • Photochromic ligand
  • Photolipid
  • Photopharmacology
  • Photoswitch

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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  • Cite this

    Morstein, J., & Trauner, D. (2020). Photopharmacological control of lipid function. In D. M. Chenoweth (Ed.), Methods in Enzymology (pp. 219-232). (Methods in Enzymology; Vol. 638). Academic Press Inc.. https://doi.org/10.1016/bs.mie.2020.04.025