Photoresponsive peptoid oligomers bearing azobenzene side chains

Neel H. Shah, Kent Kirshenbaum

Research output: Contribution to journalArticlepeer-review


N-Substituted glycine peptoid oligomers were synthesized to incorporate a photoresponsive azobenzene side chain. The ability of this side chain to undergo reversible photoisomerization was established, and the cis- to trans-azobenzene thermal isomerization of this side chain was investigated. Circular dichroism studies indicated that trans- to cis-azobenzene isomerization does not significantly alter the backbone conformation in a series of peptoids thought to have well-defined structures.

Original languageEnglish (US)
Pages (from-to)2516-2521
Number of pages6
JournalOrganic and Biomolecular Chemistry
Issue number14
StatePublished - 2008

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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