TY - JOUR
T1 - Physical activity and mortality in women in the Framingham Heart Study
AU - Sherman, Scott E.
AU - D'Agostino, Ralph B.
AU - Cobb, Janet L.
AU - Kannel, William B.
N1 - Funding Information:
Veterans Affairs University of dSection of School of Med- Supported by the Framingham Heart Study Visiting Scholar’s Fund, which includes support from the National Heart, Lung, and Blood Institute; ICI Pharma; Merck, Sharp, and Dohme; and Pfizer Inc. Received for publication Dec. 13, 1993; accepted Dec. 28, 1993. Reprint requests: Scott E. Sherman, MD, PACE Center - OOPG, Veterans Affairs Medical Center, 16111 Plummer St., Sepulveda, CA 91343. Copyright ‘9 1994 by Mosby-Year Book, Inc. OOOZ-8703/94/$3.00 +0 4/l/58131
PY - 1994/11
Y1 - 1994/11
N2 - Men who are more active live longer, but it is not clear if the same is true for women. We monitored 1404 women aged 50 to 74 who were free of cardiovascular disease. We assessed physical activity levels and ranked subjects into quartiles. After 16 years, 319 (23%) women had died. The relative risk of mortality, compared to the least active quartile, was as follows: second quartile, 0.95 (95% confidence interval [Cl] 0.72 to 1.26); third quartile, 0.63 (95% Cl 0.46 to 0.86); most active quartile, 0.67 (95% Cl 0.48 to 0.92). The relative risks were not changed by adjustment for cardiac risk factors, chronic obstructive pulmonary disease, or cancer or by excluding all subjects who died in the first 6 years (to eliminate occult disease at baseline). There was no association between activity levels and cardiovascular morbidity or mortality. We conclude that women who were more active lived longer; this effect was not the result of decreased cardiovascular disease.
AB - Men who are more active live longer, but it is not clear if the same is true for women. We monitored 1404 women aged 50 to 74 who were free of cardiovascular disease. We assessed physical activity levels and ranked subjects into quartiles. After 16 years, 319 (23%) women had died. The relative risk of mortality, compared to the least active quartile, was as follows: second quartile, 0.95 (95% confidence interval [Cl] 0.72 to 1.26); third quartile, 0.63 (95% Cl 0.46 to 0.86); most active quartile, 0.67 (95% Cl 0.48 to 0.92). The relative risks were not changed by adjustment for cardiac risk factors, chronic obstructive pulmonary disease, or cancer or by excluding all subjects who died in the first 6 years (to eliminate occult disease at baseline). There was no association between activity levels and cardiovascular morbidity or mortality. We conclude that women who were more active lived longer; this effect was not the result of decreased cardiovascular disease.
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U2 - 10.1016/0002-8703(94)90583-5
DO - 10.1016/0002-8703(94)90583-5
M3 - Article
C2 - 7942478
AN - SCOPUS:0028090348
SN - 0002-8703
VL - 128
SP - 879
EP - 884
JO - American Heart Journal
JF - American Heart Journal
IS - 5
ER -