TY - GEN
T1 - Physical and chemical characterization of synthetic bone mineral ink for robocasting applications
AU - Eckstein, Daniel
AU - Rivera, Cristobal
AU - Mijares, Dindo
AU - Coelho, Paulo G.
AU - Witek, Lukasz
N1 - Publisher Copyright:
© 2019 Omnipress - All rights reserved.
PY - 2019
Y1 - 2019
N2 - Introduction: Yearly, millions of individuals suffer from bone defects caused by trauma or congenital disease1. The “gold standard” is to fill these boney defects with an autologous bone graft, however, issues of availability, morbidity, secondary surgical site and customizability have lead to the use of synthetic grafting modalities2. The novel formulation of Synthetic Bone Mineral (SBM) is a viable option as a synthetic graft material. SBM is a carbonated hydroxyapatite with ionic substitutions of Zinc, chloride, fluoride, and magnesium, which closely mimics the chemistry of biological apatite3. Robocasting technology offers the flexibility in bone graft customization, geometry and composition. Our team has leveraged 3D printing technology to manufacture custom scaffolds using various bioactive ceramic materials without the need for a mold4. The objective of this work was to first synthesize a colloidal gel composed of SBM, then which would be suitable for Robocasting applications and characterize it chemically and mechanically.
AB - Introduction: Yearly, millions of individuals suffer from bone defects caused by trauma or congenital disease1. The “gold standard” is to fill these boney defects with an autologous bone graft, however, issues of availability, morbidity, secondary surgical site and customizability have lead to the use of synthetic grafting modalities2. The novel formulation of Synthetic Bone Mineral (SBM) is a viable option as a synthetic graft material. SBM is a carbonated hydroxyapatite with ionic substitutions of Zinc, chloride, fluoride, and magnesium, which closely mimics the chemistry of biological apatite3. Robocasting technology offers the flexibility in bone graft customization, geometry and composition. Our team has leveraged 3D printing technology to manufacture custom scaffolds using various bioactive ceramic materials without the need for a mold4. The objective of this work was to first synthesize a colloidal gel composed of SBM, then which would be suitable for Robocasting applications and characterize it chemically and mechanically.
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M3 - Conference contribution
AN - SCOPUS:85065451447
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
SP - 919
BT - Society for Biomaterials Annual Meeting and Exposition 2019
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -