Physiological bone remodeling: Systemic regulation and growth factor involvement

Jawed A. Siddiqui, Nicola C. Partridge

Research output: Contribution to journalReview articlepeer-review


Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial for sustaining bone mass and systemic mineral homeostasis. This review highlights recent work on physiological bone remodeling and discusses our knowledge of how systemic and growth factors regulate this process.

Original languageEnglish (US)
Pages (from-to)233-245
Number of pages13
Issue number3
StatePublished - May 2016

ASJC Scopus subject areas

  • Physiology


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