TY - JOUR
T1 - Plasmodium vivax in India
AU - Joshi, Hema
AU - Prajapati, Surendra K.
AU - Verma, Anju
AU - Kang'a, Simon
AU - Carlton, Jane M.
N1 - Funding Information:
J.M.C and H.J. are supported with funds from a Fogarty International Center Global Infectious Disease training grant (1D43TW007884–01). The content of this review is solely the responsibility of the authors and does not necessarily represent the official views of the Fogarty International Center or the National Institutes of Health. H.J. is thankful to Prof. A.P. Dash, Director, National Institute of Malaria Research for his constant encouragement and support. Thanks are also owed to staff members of Genetics and Molecular Biology Laboratory of NIMR for their cooperation.
PY - 2008/5
Y1 - 2008/5
N2 - Four Plasmodium species cause malaria in humans: Plasmodium vivax is the most widespread and results in pronounced morbidity. India (population >1 billion) is a major contributor to the burden of vivax malaria. With a resurgence in interest concerning the neglected burden of vivax malaria and the completion of the P. vivax genome, it is timely to review what is known concerning P. vivax in India. The P. vivax population is highly diverse in terms of relapse patterns, drug response and clinical profiles, and highly genetically variable according to studies of antigen genes, isoenzyme markers and microsatellites. The unique epidemiology of malaria in India, where P. vivax predominates over Plasmodium falciparum, renders this location ideal for studying the dynamics of co-infection.
AB - Four Plasmodium species cause malaria in humans: Plasmodium vivax is the most widespread and results in pronounced morbidity. India (population >1 billion) is a major contributor to the burden of vivax malaria. With a resurgence in interest concerning the neglected burden of vivax malaria and the completion of the P. vivax genome, it is timely to review what is known concerning P. vivax in India. The P. vivax population is highly diverse in terms of relapse patterns, drug response and clinical profiles, and highly genetically variable according to studies of antigen genes, isoenzyme markers and microsatellites. The unique epidemiology of malaria in India, where P. vivax predominates over Plasmodium falciparum, renders this location ideal for studying the dynamics of co-infection.
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U2 - 10.1016/j.pt.2008.01.007
DO - 10.1016/j.pt.2008.01.007
M3 - Review article
C2 - 18403267
AN - SCOPUS:42749084383
SN - 1471-4922
VL - 24
SP - 228
EP - 235
JO - Trends in Parasitology
JF - Trends in Parasitology
IS - 5
ER -