Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution

S. I. Shopova, R. Rajmangal, S. Holler, S. Arnold

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe and demonstrate a physical mechanism that substantially enhances the label-free sensitivity of a Whispering-Gallery-Mode biosensor for the detection of individual nanoparticles in aqueous solution. It involves the interaction of dielectric nanoparticle in an equatorial carousel orbit with a plasmonic nanoparticle bound on the orbital path. As a 60 nm dielectric particle parks on plasmonic hot spots we observe frequency shifts that are considerably enhanced consistent with a simple reactive model. Using the same model the label free detection of a single bovine serum albumin (BSA) molecule is projected.

Original languageEnglish (US)
Title of host publicationPhotonic Microdevices/Microstructures for Sensing IV
DOIs
StatePublished - 2012
EventPhotonic Microdevices/Microstructures for Sensing IV - Baltimore, MD, United States
Duration: Apr 26 2012Apr 27 2012

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8376
ISSN (Print)0277-786X

Other

OtherPhotonic Microdevices/Microstructures for Sensing IV
CountryUnited States
CityBaltimore, MD
Period4/26/124/27/12

Keywords

  • biosensing
  • plasmonic enhancement
  • whispering-gallery-mode

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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