Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution

S. I. Shopova; R. Rajmangal; S. Holler; S. Arnold

doi:10.1117/12.920614

Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution

S. I. Shopova, R. Rajmangal, S. Holler, S. Arnold

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We describe and demonstrate a physical mechanism that substantially enhances the label-free sensitivity of a Whispering-Gallery-Mode biosensor for the detection of individual nanoparticles in aqueous solution. It involves the interaction of dielectric nanoparticle in an equatorial carousel orbit with a plasmonic nanoparticle bound on the orbital path. As a 60 nm dielectric particle parks on plasmonic hot spots we observe frequency shifts that are considerably enhanced consistent with a simple reactive model. Using the same model the label free detection of a single bovine serum albumin (BSA) molecule is projected.

Original language	English (US)
Title of host publication	Photonic Microdevices/Microstructures for Sensing IV
DOIs	https://doi.org/10.1117/12.920614
State	Published - 2012
Event	Photonic Microdevices/Microstructures for Sensing IV - Baltimore, MD, United States Duration: Apr 26 2012 → Apr 27 2012

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	8376
ISSN (Print)	0277-786X

Other

Other	Photonic Microdevices/Microstructures for Sensing IV
Country/Territory	United States
City	Baltimore, MD
Period	4/26/12 → 4/27/12

Keywords

biosensing
plasmonic enhancement
whispering-gallery-mode

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Access to Document

10.1117/12.920614

Cite this

Shopova, S. I., Rajmangal, R., Holler, S., & Arnold, S. (2012). Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. In Photonic Microdevices/Microstructures for Sensing IV Article 837605 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 8376). https://doi.org/10.1117/12.920614

Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. / Shopova, S. I.; Rajmangal, R.; Holler, S. et al.
Photonic Microdevices/Microstructures for Sensing IV. 2012. 837605 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 8376).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Shopova, SI, Rajmangal, R, Holler, S & Arnold, S 2012, Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution. in Photonic Microdevices/Microstructures for Sensing IV., 837605, Proceedings of SPIE - The International Society for Optical Engineering, vol. 8376, Photonic Microdevices/Microstructures for Sensing IV, Baltimore, MD, United States, 4/26/12. https://doi.org/10.1117/12.920614

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abstract = "We describe and demonstrate a physical mechanism that substantially enhances the label-free sensitivity of a Whispering-Gallery-Mode biosensor for the detection of individual nanoparticles in aqueous solution. It involves the interaction of dielectric nanoparticle in an equatorial carousel orbit with a plasmonic nanoparticle bound on the orbital path. As a 60 nm dielectric particle parks on plasmonic hot spots we observe frequency shifts that are considerably enhanced consistent with a simple reactive model. Using the same model the label free detection of a single bovine serum albumin (BSA) molecule is projected.",

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AB - We describe and demonstrate a physical mechanism that substantially enhances the label-free sensitivity of a Whispering-Gallery-Mode biosensor for the detection of individual nanoparticles in aqueous solution. It involves the interaction of dielectric nanoparticle in an equatorial carousel orbit with a plasmonic nanoparticle bound on the orbital path. As a 60 nm dielectric particle parks on plasmonic hot spots we observe frequency shifts that are considerably enhanced consistent with a simple reactive model. Using the same model the label free detection of a single bovine serum albumin (BSA) molecule is projected.

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Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection in aqueous solution

Abstract

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Keywords

ASJC Scopus subject areas

Access to Document

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