Plasmonic enhancement of a whispering-gallery-mode biosensor for single nanoparticle detection

S. I. Shopova, R. Rajmangal, S. Holler, S. Arnold

Research output: Contribution to journalArticlepeer-review

Abstract

We describe and demonstrate a physical mechanism that substantially enhances the label-free sensitivity of a whispering-gallery-mode biosensor for the detection of individual nanoparticles in aqueous solution. It involves the interaction of dielectric nanoparticle in an equatorial carousel orbit with a plasmonic nanoparticle bound at the microparticle's equator. As the dielectric particle parks to hot spots on the plasmonic particle we observe frequency shifts that are enhanced by a factor of 4, consistent with a simple reactive model. Once optimized the enhancement by this mechanism should exceed several orders of magnitude, putting individual protein within reach.

Original languageEnglish (US)
Article number243104
JournalApplied Physics Letters
Volume98
Issue number24
DOIs
StatePublished - Jun 13 2011

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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