Point detection of bacterial and viral pathogens using oral samples

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Oral samples, including saliva, offer an attractive alternative to serum or urine for diagnostic testing. This is particularly true for point-of-use detection systems. The various types of oral samples that have been reported in the literature are presented here along with the wide variety of analytes that have been measured in saliva and other oral samples. The paper focuses on utilizing point-detection of infectious disease agents, and presents work from our group on a rapid test for multiple bacterial and viral pathogens by monitoring a series of targets. It is thus possible in a single oral sample to identify multiple pathogens based on specific antigens, nucleic acids, and host antibodies to those pathogens. The value of such a technology for detecting agents of bioterrorism at remote sites is discussed.

Original languageEnglish (US)
Title of host publicationOptics and Photonics in Global Homeland Security IV
StatePublished - 2008
EventOptics and Photonics in Global Homeland Security IV - Orlando, FL, United States
Duration: Mar 17 2008Mar 20 2008

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherOptics and Photonics in Global Homeland Security IV
Country/TerritoryUnited States
CityOrlando, FL


  • Bacteria
  • Microfluidic
  • Oral
  • Pathogen
  • Pathogens
  • Point-of-care (POC)
  • Saliva
  • Up-Converting Phosphor (UCP)
  • Viral

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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