Polymer-population mapping and localization in the space of phenotypes

Edo Kussell, Stanislas Leibler, Alexander Grosberg

Research output: Contribution to journalArticlepeer-review

Abstract

We present a mapping between the thermodynamics of an ideal heteropolymer in an external field and the dynamics of structured populations in fluctuating environments. We employ a population model in which individuals may adopt different phenotypes, each of which may be optimal in a different environment. Using this mapping, we develop a path integral formulation for populations and predict the existence of a biological counterpart for the well-known heteropolymer localization phase transition.

Original languageEnglish (US)
Article number068101
JournalPhysical Review Letters
Volume97
Issue number6
DOIs
StatePublished - 2006

ASJC Scopus subject areas

  • General Physics and Astronomy

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