Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View across the International Centers of Excellence for Malaria Research

Jane M. Carlton; Sarah K. Volkman; Swapna Uplekar; Daniel N. Hupalo; João Marcelo Pereira Alves; Liwang Cui; Martin Donnelly; David S. Roos; Omar S. Harb; Monica Acosta; Andrew Read; Paulo E M Ribolla; Om P. Singh; Neena Valecha; Samuel C. Wassmer; Marcelo Ferreira; Ananias A. Escalante

doi:10.4269/ajtmh.15-0049

Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View across the International Centers of Excellence for Malaria Research

Jane M. Carlton, Sarah K. Volkman, Swapna Uplekar, Daniel N. Hupalo, João Marcelo Pereira Alves, Liwang Cui, Martin Donnelly, David S. Roos, Omar S. Harb, Monica Acosta, Andrew Read, Paulo E M Ribolla, Om P. Singh, Neena Valecha, Samuel C. Wassmer, Marcelo Ferreira, Ananias A. Escalante

Research output: Contribution to journal › Article › peer-review

Abstract

The study of the three protagonists in malaria—the Plasmodium parasite, the Anopheles mosquito, and the human host—is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world.

Original language	English (US)
Pages (from-to)	87-98
Number of pages	12
Journal	American Journal of Tropical Medicine and Hygiene
Volume	93
Issue number	3
DOIs	https://doi.org/10.4269/ajtmh.15-0049
State	Published - Sep 2015

ASJC Scopus subject areas

Parasitology
Infectious Diseases
Virology

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10.4269/ajtmh.15-0049

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Carlton, J. M., Volkman, S. K., Uplekar, S., Hupalo, D. N., Pereira Alves, J. M., Cui, L., Donnelly, M., Roos, D. S., Harb, O. S., Acosta, M., Read, A., Ribolla, P. E. M., Singh, O. P., Valecha, N., Wassmer, S. C., Ferreira, M., & Escalante, A. A. (2015). Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View across the International Centers of Excellence for Malaria Research. American Journal of Tropical Medicine and Hygiene, 93(3), 87-98. https://doi.org/10.4269/ajtmh.15-0049

Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View across the International Centers of Excellence for Malaria Research. / Carlton, Jane M.; Volkman, Sarah K.; Uplekar, Swapna et al.
In: American Journal of Tropical Medicine and Hygiene, Vol. 93, No. 3, 09.2015, p. 87-98.

Research output: Contribution to journal › Article › peer-review

Carlton, JM, Volkman, SK, Uplekar, S, Hupalo, DN, Pereira Alves, JM, Cui, L, Donnelly, M, Roos, DS, Harb, OS, Acosta, M, Read, A, Ribolla, PEM, Singh, OP, Valecha, N, Wassmer, SC, Ferreira, M & Escalante, AA 2015, 'Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View across the International Centers of Excellence for Malaria Research', American Journal of Tropical Medicine and Hygiene, vol. 93, no. 3, pp. 87-98. https://doi.org/10.4269/ajtmh.15-0049

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abstract = "The study of the three protagonists in malaria—the Plasmodium parasite, the Anopheles mosquito, and the human host—is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world.",

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AU - Donnelly, Martin

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Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View across the International Centers of Excellence for Malaria Research

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