TY - JOUR
T1 - Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria
T2 - A View Across the International Centers of Excellence for Malaria Research
AU - Carlton, Jane M.
AU - Volkman, Sarah K.
AU - Uplekar, Swapna
AU - Hupalo, Daniel N.
AU - Pereira Alves, João Marcelo
AU - Cui, Liwang
AU - Donnelly, Martin
AU - Roos, David S.
AU - Harb, Omar S.
AU - Acosta, Monica
AU - Read, Andrew
AU - Ribolla, Paulo E M
AU - Singh, Om P.
AU - Valecha, Neena
AU - Wassmer, Samuel C.
AU - Ferreira, Marcelo
AU - Escalante, Ananias A.
N1 - Publisher Copyright:
© The American Society of Tropical Medicine and Hygiene.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - The study of the three protagonists in malaria-the Plasmodium parasite, the Anopheles mosquito, and the human host-is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world.
AB - The study of the three protagonists in malaria-the Plasmodium parasite, the Anopheles mosquito, and the human host-is key to developing methods to control and eventually eliminate the disease. Genomic technologies, including the recent development of next-generation sequencing, enable interrogation of this triangle to an unprecedented level of scrutiny, and promise exciting progress toward real-time epidemiology studies and the study of evolutionary adaptation. We discuss the use of genomics by the International Centers of Excellence for Malaria Research, a network of field sites and laboratories in malaria-endemic countries that undertake cutting-edge research, training, and technology transfer in malarious countries of the world.
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U2 - 10.4269/ajtmh.15-0049
DO - 10.4269/ajtmh.15-0049
M3 - Article
C2 - 26259940
AN - SCOPUS:84965086957
VL - 93
SP - 87
EP - 98
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 3
ER -