Potassium Channels: Symmetric, Selective, and Sensitive

Dirk Trauner

Research output: Contribution to journalReview articlepeer-review

Abstract

Crystallized and elucidated: Our understanding of the basic functions of ion channels-the selective guidance of ions through cell membranes and the control of this process by "gates"-is derived to a large extent from the contributions of Roderick MacKinnon, who was awarded a Nobel Prize this year for his work. The picture shows the X-ray crystal structure of the prokaryotic potassium channel KcsA (blue: K+ ions, red: carbonyl groups of the peptide backbone and water molecules).

Original languageEnglish (US)
Pages (from-to)5671-5675
Number of pages5
JournalAngewandte Chemie - International Edition
Volume42
Issue number46
DOIs
StatePublished - Dec 1 2003

Keywords

  • Ion channels
  • Membranes
  • Neurobiology
  • Protein structures
  • Structure elucidation

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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