Potassium Channels: Symmetric, Selective, and Sensitive

Dirk Trauner

doi:10.1002/anie.200301724

Potassium Channels: Symmetric, Selective, and Sensitive

Dirk Trauner

Chemistry

Research output: Contribution to journal › Review article › peer-review

Abstract

Crystallized and elucidated: Our understanding of the basic functions of ion channels-the selective guidance of ions through cell membranes and the control of this process by "gates"-is derived to a large extent from the contributions of Roderick MacKinnon, who was awarded a Nobel Prize this year for his work. The picture shows the X-ray crystal structure of the prokaryotic potassium channel KcsA (blue: K⁺ ions, red: carbonyl groups of the peptide backbone and water molecules).

Original language	English (US)
Pages (from-to)	5671-5675
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	42
Issue number	46
DOIs	https://doi.org/10.1002/anie.200301724
State	Published - Dec 1 2003

Keywords

Ion channels
Membranes
Neurobiology
Protein structures
Structure elucidation

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200301724

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AB - Crystallized and elucidated: Our understanding of the basic functions of ion channels-the selective guidance of ions through cell membranes and the control of this process by "gates"-is derived to a large extent from the contributions of Roderick MacKinnon, who was awarded a Nobel Prize this year for his work. The picture shows the X-ray crystal structure of the prokaryotic potassium channel KcsA (blue: K+ ions, red: carbonyl groups of the peptide backbone and water molecules).

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KW - Membranes

KW - Neurobiology

KW - Protein structures

KW - Structure elucidation

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Potassium Channels: Symmetric, Selective, and Sensitive

Abstract

Keywords

ASJC Scopus subject areas

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