Potential mechanism for the laser-fluoride effect on enamel demineralization

Y. Liu; C. Y.S. Hsu; C. M.J. Teo; S. H. Teoh

doi:10.1177/0022034512466412

Potential mechanism for the laser-fluoride effect on enamel demineralization

Y. Liu, C. Y.S. Hsu, C. M.J. Teo, S. H. Teoh

Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Laser-induced prevention of dental caries has been studied extensively. However, the cariostatic mechanisms of a combined fluoride-laser treatment are not well-understood. Using micro- computed tomography (micro-CT), we quantified the effect of fluoride and/or Er:YAG laser treatment on enamel demineralization. The mean mineral loss (%/V) for each group was 4,870 ± 1,434 (fluoride followed by laser treatment), 6,341 ± 2,204 (laser treatment), 7,669 ± 2,255 (fluoride treatment), and 10,779 ± 2,936 (control). The preventive effect of the laser (p < 0.001) and fluoride (p = 0.010) treatment was statistically significant. Characterized by micro-x-ray diffraction (XRD) analysis, the significant contraction in the a-axis after both laser and combined laser/fluoride treatment was revealed (both p < 0.05). In conclusion, subablative low-energy Er:YAG laser irradiation following fluoride treatment may instantaneously transform enamel hydroxyapatite into fluoridated hydroxyapatite to reduce enamel solubility as a preventive treatment for enamel demineralization.

Original language	English (US)
Pages (from-to)	71-75
Number of pages	5
Journal	Journal of dental research
Volume	92
Issue number	1
DOIs	https://doi.org/10.1177/0022034512466412
State	Published - Jan 2013

Keywords

caries
low energy
micro-CT
microXRD
mineral loss
non-invasive

ASJC Scopus subject areas

Dentistry(all)

Access to Document

10.1177/0022034512466412

Cite this

@article{9ad5cb41afee413fbddc10dbac8335a0,

title = "Potential mechanism for the laser-fluoride effect on enamel demineralization",

abstract = "Laser-induced prevention of dental caries has been studied extensively. However, the cariostatic mechanisms of a combined fluoride-laser treatment are not well-understood. Using micro- computed tomography (micro-CT), we quantified the effect of fluoride and/or Er:YAG laser treatment on enamel demineralization. The mean mineral loss (%/V) for each group was 4,870 ± 1,434 (fluoride followed by laser treatment), 6,341 ± 2,204 (laser treatment), 7,669 ± 2,255 (fluoride treatment), and 10,779 ± 2,936 (control). The preventive effect of the laser (p < 0.001) and fluoride (p = 0.010) treatment was statistically significant. Characterized by micro-x-ray diffraction (XRD) analysis, the significant contraction in the a-axis after both laser and combined laser/fluoride treatment was revealed (both p < 0.05). In conclusion, subablative low-energy Er:YAG laser irradiation following fluoride treatment may instantaneously transform enamel hydroxyapatite into fluoridated hydroxyapatite to reduce enamel solubility as a preventive treatment for enamel demineralization.",

keywords = "caries, low energy, micro-CT, microXRD, mineral loss, non-invasive",

author = "Y. Liu and Hsu, {C. Y.S.} and Teo, {C. M.J.} and Teoh, {S. H.}",

note = "Funding Information: This study was supported by Singapore Biomedical Research Council grant R222-000-015-305 and by Ministry of Education grants R-222-000-028-112 and R222-000-031-112 . ",

year = "2013",

month = jan,

doi = "10.1177/0022034512466412",

language = "English (US)",

volume = "92",

pages = "71--75",

journal = "Journal of dental research",

issn = "0022-0345",

publisher = "SAGE Publications Inc.",

number = "1",

}

TY - JOUR

T1 - Potential mechanism for the laser-fluoride effect on enamel demineralization

AU - Liu, Y.

AU - Hsu, C. Y.S.

AU - Teo, C. M.J.

AU - Teoh, S. H.

N1 - Funding Information: This study was supported by Singapore Biomedical Research Council grant R222-000-015-305 and by Ministry of Education grants R-222-000-028-112 and R222-000-031-112 .

PY - 2013/1

Y1 - 2013/1

N2 - Laser-induced prevention of dental caries has been studied extensively. However, the cariostatic mechanisms of a combined fluoride-laser treatment are not well-understood. Using micro- computed tomography (micro-CT), we quantified the effect of fluoride and/or Er:YAG laser treatment on enamel demineralization. The mean mineral loss (%/V) for each group was 4,870 ± 1,434 (fluoride followed by laser treatment), 6,341 ± 2,204 (laser treatment), 7,669 ± 2,255 (fluoride treatment), and 10,779 ± 2,936 (control). The preventive effect of the laser (p < 0.001) and fluoride (p = 0.010) treatment was statistically significant. Characterized by micro-x-ray diffraction (XRD) analysis, the significant contraction in the a-axis after both laser and combined laser/fluoride treatment was revealed (both p < 0.05). In conclusion, subablative low-energy Er:YAG laser irradiation following fluoride treatment may instantaneously transform enamel hydroxyapatite into fluoridated hydroxyapatite to reduce enamel solubility as a preventive treatment for enamel demineralization.

AB - Laser-induced prevention of dental caries has been studied extensively. However, the cariostatic mechanisms of a combined fluoride-laser treatment are not well-understood. Using micro- computed tomography (micro-CT), we quantified the effect of fluoride and/or Er:YAG laser treatment on enamel demineralization. The mean mineral loss (%/V) for each group was 4,870 ± 1,434 (fluoride followed by laser treatment), 6,341 ± 2,204 (laser treatment), 7,669 ± 2,255 (fluoride treatment), and 10,779 ± 2,936 (control). The preventive effect of the laser (p < 0.001) and fluoride (p = 0.010) treatment was statistically significant. Characterized by micro-x-ray diffraction (XRD) analysis, the significant contraction in the a-axis after both laser and combined laser/fluoride treatment was revealed (both p < 0.05). In conclusion, subablative low-energy Er:YAG laser irradiation following fluoride treatment may instantaneously transform enamel hydroxyapatite into fluoridated hydroxyapatite to reduce enamel solubility as a preventive treatment for enamel demineralization.

KW - caries

KW - low energy

KW - micro-CT

KW - microXRD

KW - mineral loss

KW - non-invasive

UR - http://www.scopus.com/inward/record.url?scp=84870951645&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870951645&partnerID=8YFLogxK

U2 - 10.1177/0022034512466412

DO - 10.1177/0022034512466412

M3 - Article

C2 - 23114033

AN - SCOPUS:84870951645

SN - 0022-0345

VL - 92

SP - 71

EP - 75

JO - Journal of dental research

JF - Journal of dental research

IS - 1

ER -

Potential mechanism for the laser-fluoride effect on enamel demineralization

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this