Precision accelerated orthodontics: How micro-osteoperforations and vibration trigger inflammation to optimize tooth movement

In this chapter, we take you on our journey through the latest scientific evidence on bone remodeling and orthodontic tooth movement that led to the development of the biphasic theory of tooth movement and how we translated this new understanding into clinically useful tools to optimize and accelerate orthodontic tooth movement. According to the biphasic theory, an orthodontic force causes two sequential phases of bone remodeling, the catabolic phase, followed by the anabolic phase. In this chapter, we discuss how we were able to stimulate and harness this bone remodeling system to accelerate orthodontic tooth movement precisely, create biological anchorage, optimize the type of movement, and move teeth into areas of atrophic bone. Our journey from basic science to the clinic is chronicled by our development of micro-osteoperforations and vibration protocols that demonstrate how a sound understanding of the biology of teeth movement is translated into safe, minimally invasive, and predictable protocols for precision accelerated orthodontics.