@inproceedings{c27b982b10dc41e09d8fc3e659ba3e52,
title = "Preliminary study monitoring hemodynamics using dynamic vascular optical spectroscopy during a surgical intervention",
abstract = "Peripheral arterial disease (PAD) affects an estimated 8.5 million people in the United States. PAD is caused by atherosclerosis, which is a narrowing of the arteries due to plaque build-up. Patients with a severe presentation of the disease often require a surgical intervention to reopen the arteries and restore blood flow to the affected areas. During the intervention, physicians often monitor the progress of the intervention using contrast angiography. The process requires a contrast agent and high radiation doses. Our lab has proposed the use of dynamic vascular optical spectroscopy (DVOS) as a non-invasive, non-iodizing method to track changes in the arteries during an intervention. In this preliminary study, we found that the DVOS signal changes in response to intervention techniques such as balloon inflations and deflations. For our trial subject, we saw on average a 19.5% change in total hemoglobin concentration (HbT) due to injection of a contrast agent prior to balloon inflation and on average a 26.6% change in HbT due to injection of a contrast agent after a sequence of balloon inflations and deflations. The data suggest that DVOS can monitor vascular health and blood perfusion in arteries in real-time during a surgical intervention.",
keywords = "dynamic vascular spectroscopy, monitoring, peripheral arterial disease (PAD), surgery",
author = "N. Maheshwari and A. Marone and Kim, {S. H.K.} and Bajakian, {D. R.} and Hielscher, {A. H.}",
note = "Funding Information: This work was supported in part through grants from the National Heart, Blood, and uL ng Institute (NHLBI -1R01 -H11L 5336-01), Wallace H. Coulter Foundation, Society of Vascular Surgery and Columbia University – Translational esR earch Fellowship , and New York University Tandon School of Engineering. Funding Information: This work was supported in part through grants from the National Heart, Blood, and Lung Institute (NHLBI-1R01-HL115336-01), Wallace H. Coulter Foundation, Society of Vascular Surgery and Columbia University – Translational Research Fellowship, and New York University Tandon School of Engineering. Publisher Copyright: {\textcopyright} 2023 SPIE.; Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics 2023 ; Conference date: 30-01-2023 Through 31-01-2023",
year = "2023",
doi = "10.1117/12.2650329",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Cote, {Gerard L.}",
booktitle = "Optical Diagnostics and Sensing XXIII",
}