Problems With Using Polygenic Scores to Select Embryos

Patrick Turley, Michelle N. Meyer, Nancy Wang, David Cesarini, Evelynn Hammonds, Alicia R. Martin, Benjamin M. Neale, Heidi L. Rehm, Louise Wilkins-Haug, Daniel J. Benjamin, Steven Hyman, David Laibson, Peter M. Visscher

    Research output: Contribution to journalArticlepeer-review


    Embryo selection based on polygenic scores (ESPS) is the principle wherein one can select individualized embryos to transfer as part of in vitro fertilization based on predictions of health and other outcomes derived from genome-wide association studies (GWASs). The majority of human traits including physical characteristics and risk for disease are influenced by cumulative differences in genetic variants.

    Original languageEnglish (US)
    Pages (from-to)609-610
    Number of pages2
    JournalObstetrical and Gynecological Survey
    Issue number10
    StatePublished - Oct 1 2021

    ASJC Scopus subject areas

    • Obstetrics and Gynecology


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