Programing the formation of DNA and PNA quadruplexes by π-π-stacking interactions

Sourav Saha, Jianfeng Cai, Daniel Eiler, Andrew D. Hamilton

Research output: Contribution to journalArticlepeer-review

Abstract

Guanine (G) rich G4T4G4 DNA and homologous PNA strands tend to form antiparallel dimeric quadruplexes. In contrast, the same DNA strands carrying planar aromatic 5′-residues preferentially form parallel DNA quadruplex. Conformation and composition of the DNA quadruplexes can be programed by π-π-stacking interaction exerted by the 5′-residues.

Original languageEnglish (US)
Pages (from-to)1685-1687
Number of pages3
JournalChemical Communications
Volume46
Issue number10
DOIs
StatePublished - 2010

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Programing the formation of DNA and PNA quadruplexes by π-π-stacking interactions'. Together they form a unique fingerprint.

Cite this