Abstract
The propagation of activity is studied in a spatially structured network model of γ-aminobutyric acid-containing (GABAergic) neurons exhibiting postinhibitory rebound. In contrast to excitatory-coupled networks, recruitment spreads very slowly because cells fire only after the postsynaptic conductance decays, and with two possible propagation models. If the connection strength decreases monotonically with distance (on-center), then propagation occurs in a discontinuous manner. If the self- and nearby connections are absent reversal potential can result in depolarization- mediated eaves that are 25 times faster. Functional and developmental roles for these behaviors and implications for thalamic circuitry are suggested.
Original language | English (US) |
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Pages (from-to) | 1351-1355 |
Number of pages | 5 |
Journal | Science |
Volume | 279 |
Issue number | 5355 |
DOIs | |
State | Published - Feb 27 1998 |
ASJC Scopus subject areas
- General